Bacterial bone infections induce a massive inflammatory response. However, the inflammatory composition in bone tissue emerged from bacterial infections and its impact on the final healing outcome is limited and the current knowledge is primarily based on in vitro studies.  

We use microdialysis to explore inflammatory molecules in the extracellular fluid of target tissues. Using a human proximity extension assay, we estimate the local concentrations of the protein profiles comprised in the Olink Inflammatory panel¹. 

_{1 BioXpedia A/S, Aarhus, Denmark}