Team
Research experience
In vitro microdialysis calibration, in vivo microdialysis sampling of antimicrobial and chemotherapeutic concentrations in bone, abdominal organs, and soft tissues in both porcine models and clinical studies. Expert in orthopaedic hand infections.
Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2016.
Research experience
Refined the microdialysis method for sampling of antibiotic concentrations, ischemic metabolites and inflammatory markers in bone tissue in different orthopaedic settings. Expertise in orthopaedic prostethic joint infections.
Founding member of the Aarhus Microdialysis Group in 2013.
Research experience
In vitro and in vivo microdialysis calibration, in vivo Microdialysis sampling of ischemic marker, antimicrobial and chemotherapeutic concentrations in bone, abdominal organs, and soft tissues in both porcine and clinical studies. Expert in antibiotic tissue pharmacokinetics.
Founding member of Aarhus Denmark Microdialysis Research (ADMIRE) in 2013.
Research experience
In vitro and in vivo microdialysis calibration, in vivo microdialysis sampling of ischemic marker, antimicrobial and chemotherapeutic concentrations in bone, abdominal organs, and soft tissues in both porcine models and clinical studies. Expert in antibiotic tissue pharmacokinetics.
Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2014.
Research experience
In vitro microdialysis calibration, in vivo microdialysis sampling of antimicrobial concentrations and chemotherapeutics in bone and soft tissues in both a porcine model and clinical studies. Specialized in chemotherapy.
Research year 2019-2020. PhD 2021-2024. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2018.
Research experience
In vitro microdialysis calibration, cisplatin and carboplatin application during HIPEC procedure combined with cytoreductive surgery in recurrent ovarian cancer in large procine model, in vivo microdialysis sampling of cisplatin and animal surgery.
Member of Aarhus Denmark Microdialysis Group (ADMIRE) since 2020.
Research experience
In vitro microdialysis calibration, in vivo microdialysis sampling of antimicrobial concentrations in bone and soft tissues in porcine models and animal surgery. Rifampicin, moxifloxacin, meropenem and vancomycin pharmacokinetics. Specialized in experimental spinal and tibial models. Development of a novel porcine flap model.
Research year 2018-2019. Member of Aarhus Denmark Microdialysis Research since 2017.
Research experience
Experimental animal studies using microdialysis. In vivo sampling of antimicrobial concentrations in bone and soft tissues in a porcine model with a focus on flucloxacillin pharmacokinetics and concentrations after oral and intravenous administration.
Research year 2019-2020. Member of Aarhus Denmark Microdialysis Research since 2019.
Research experience
Orthopaedic and pharmacological in vivo experimental and clinical research; Investigation of prophylactic cefuroxime treatment, mastering the microdialysis technique. Planning and conducting experimental porcine and clinical patient studies in a shoulder arthroplasty surgery model. Evaluation of microdialysis data and in situ ischemic metabolites.
Research experience
In vitro microdialysis calibration. Microdialysis, sampling of antimicrobial concentrations in bone and soft tissues in a porcine model with focus on piperacillin pharmacokinetics and evaluation of in situ ischemic metabolites. Specialized in experimental spinal and tibial models.
Research year student 2020-2021. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2019.
Research experience
Experience in experimental animal research using microdialysis and animal osteomyelitis model. Expertise in prophylaxis/treatment of infections related to open bone fractures and prosthetic joint infections. Focus on combination therapy of rifampicin combined with moxifloxacin, and vancomycin combined with meropenem. Specialized in experimental spinal and tibial models.
Research year student 2021-2022. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since February 2020.
Research experience
Experimental animal studies and clinical research using microdialysis. Advanced in planning and conducting antibiotic studies in porcine spinal models and clinical research in orthopaedic spinal surgery. Focus on antimicrobial prophylaxis, dosing regimens, and cefuroxime pharmacokinetics.
Research year student 2021-2022. Member of the Aarhus Denmark Microdialysis Research (ADMIRE) since 2020.
Research experience
In vitro microdialysis calibration, cisplatin and carboplatin application during HIPEC procedure combined with cytoreductive surgery in recurrent ovarian cancer in a large porcine model, in vivo microdialysis sampling of carboplatin and animal surgery. Experience with investigation of inflammatory protein markers and ischemic metabolites in peritoneal porcine tissue.
Research year student 2021-2022. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2020.
Research experience
Experience in experimental animal research using microdialysis. Currently working on in vitro calibration of penicillin and in vivo sampling of penicillin in bone and soft tissue after oral and intravenous administration in a porcine model.
Research year student 2022-2023. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2021.
Research experience
Experience in experimental animal studies using microdialysis. In vitro microdialysis calibration. In vivo sampling of antimicrobial concentrations in bone and soft tissues in a porcine model with focus on the novel antibiotic, dalbavancin. Evaluating its pharmacokinetics and concentrations in orthopedically relevant tissues.
Research year student 2022-2023. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2022.
Research experience
In vivo microdialysis sampling of antimicrobial concentrations in bone and soft tissues in a porcine model with a focus on local application of vancomycin.
Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2018.
Research experience
In vitro cell culture. RNA, DNA and protein extraction, Q-PCR, western blotting, immunohistochemistry.
Research experience
In vitro microdialysis calibration. In vivo microdialysis sampling of antimicrobials in porcine models and in clinical settings. Focus on azithromycin pharmacokinetics and concentrations in tissues related to NTM-infections.
Research year 2023-2024. Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2023
Maria B. Damsgaard Nielsen
MD graduate student, Research year student (2024-2025)
T: + 42 80 76 90
E: mabdni@au.dk
Research experience
Experimental animal research using microdialysis. In vivo sampling of antimicrobial concentrations in bone and soft tissues in a porcine model with focus on Cefepime-enmetazobactam pharmacokinetics.
Member of Aarhus Denmark Microdialysis Research (ADMIRE) since 2023.